WebPharmacological inhibition of both cystine uptake and transsulfuration combined with GPX4 inactivation resulted in tumor remission in an orthotopic MYCN-amplified … Web26 mrt. 2013 · Our aim was to investigate the potential tumor suppressive role of miR-497 in high-risk neuroblastoma. Results We determined that miR-497 expression was …
MYC activation impairs cell-intrinsic IFNγ signaling and confers ...
WebSince c-MYC is amplified in >40% ovarian tumors, our results provide the basis for repositioning amiodarone and dronedarone as novel c-MYC targeting drugs in EOC with … Web11 apr. 2024 · Medulloblastoma (MB), the most common brain tumor of the cerebellum, is a leading cause of cancer-related deaths in children. The current standard of care for MB patients involves a combination of maximal surgical resection followed by craniospinal radiation and high-dose chemotherapy [ 1, 2 ]. tergas keros
肿瘤研究领域热门基因之MYC - 知乎
Web3 mrt. 2024 · The oncogene MYC alters cellular metabolism. Medulloblastoma is the most common malignant pediatric brain tumor. MYC-amplified medulloblastoma has a poor … Web9 mei 2024 · In TCGA cohort, MYC amplification was identified in 21.2% (229/1079) and was associated with age, estrogen receptor status, progesterone receptor status, human … WebMYC as a target for cancer treatment. The MYC gene which consists of 3 paralogs, C-MYC, N-MYC and L-MYC, is one of the most frequently deregulated driver genes in human … tergase